Prescription drugs can be characterized by their enantiomer composition.
Enantiomer analysis can also be a very useful tool in the evaluation of the source of the drug. Obviously, those drugs that contain amphetamine would not give rise to methamphetamine, which can eliminate several potential sources for the drug.
, describe the profiling of contaminants found in the illicit preparation of methamphetamine as a means of identification of the source of the drug as not being legitimate. Pharmaceutical amphetamine and methamphetamine are high purity drugs that can often be separated from illicitly produced drugs that typically are not purified to the high degree seen in the legitimate pharmaceutical industry. There is much, however, that can be determined by evaluation of the drug, its metabolites, potential precursors and impurities.
Interpretation of the source of the amphetamine and/or methamphetamine is a difficult task. Cody, in Handbook of Analytical Separations, 2008 3.7.2 Source Differentiation
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